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Copper as a cofactor

Cu/Zn-superoxide dismutase and glutathione peroxidase during aging

Homozygous loss-of-function mutations in the SLC2A9 (encoding the transporter protein GLUT9) and SLC22A12 (encoding the transporter protein URAT1) genes lead to hereditary renal hypouricemia type 1 and 2, respectively [21]

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Glutathione is involved in both of those phases

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