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It is widely used in compliance with the EU Cosmetics Regulation (EC) No 1223/2009

MC1R is the receptor most relevant to pigmentation and photoprotection

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Thats exactly what semaglutide (Wegovy) and tirzepatide (Zepbound) do

These include: Those with a History of Thyroid Cancer People with a personal or family history of thyroid cancer, like medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2), should avoid semaglutide due to potential risks

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