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50,51 In a recent study, MSCs enhanced autophagy and exerted a neuroprotective effect by modulating amyloid- clearance in an AD mouse model

These neuropathological changes initiate microglia activation, neuroinflammation, progressive neuronal apoptosis, synaptic dysfunction, impairment of cholinergic neurotransmission, synaptic dysfunction, and the development of cognitive decline in AD (Chen et al

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