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The combination of L-carnitine and acetyl-L-carnitine also showed favorable results, suggesting that carnitine compounds may work through complementary pathways

doi: 10.1126/sciadv.abi6696, 88 MorlandC.AnderssonK

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In turn, the impairment in -oxidation can shift the metabolism of VPA toward predominantly peroxisomal -oxidation, resulting in excessive production and accumulation of -oxidation products, including 4-en-VPA a metabolite that is incriminated in VPA-induced hepatotoxicity