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Increasing studies have confirmed that obesity, metabolic status and gut microbiota imbalance can promote the occurrence of OA through the metabolism-inflammation-oxidative stress network, which is closely related to daily nutrition or dietary intake

Se han descrito posibles mejoras del dolor espontneo, la sensacin de pesadez, el edema fluctuante o los requerimientos de analgsicos, aunque estos hallazgos proceden de casos aislados, pequeas series no controladas y variables evaluadas fundamentalmente mediante resultados comunicados por las pacientes 8,9 , en consonancia con distintas hiptesis propuestas en revisiones narrativas 11,12