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doi: 10.2478/s11536-009-0074-x [DOI] [Google Scholar] 51

To determine whether this variant is likely to be causal, we considered all 42 variants within the 99% credible set of the association, and annotated by predicted functional consequence (Supplementary Table 9)

Receptor Downregulation Findings and Study Design Implications A well-documented finding in the research literature is that continuous IGF-1 receptor activation leads to receptor downregulation after approximately four to six weeks, reducing cellular responsiveness to further stimulation

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Months 7 through 12: Approach to optimal results for the given protocol

10.3390/cimb46050298 157 MancusoR.SicurellaM.AgostiniS.MarconiP.ClericiM