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Lean body mass is affected by the degree of calorie restriction, rate of weight loss, optimal protein intake and the presence/absence of strength training

Given this, dietary supplements may no longer be optional for many people (Johnson 2025)

However, these are often less pronounced with microdosing compared to standard dosing regimens

Additionally, older GLP-1 drugs, such as exenatide, have seen a decline in claims since the early 2010s as newer drugs were introduced

If you want a more personalized understanding of how much protein you should be taking, you can consult your doctor or a registered dietitian, who can help you narrow that down

thus, its variability has the potential to confound data interpretation