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PPAR signalinglipid oxidation and storage regulation Signals from nutrients are converted into coordinated lipid metabolism programs by ligand-activated transcription factors called peroxisome proliferatoractivated receptors (PPARs) (181, 182)

New England J Med 385(6):503515 Funding Karan Chhabra is supported by KL2 TR001446 from the National Center for Advancing Translational Sciences, National Institutes of Health

Some FDA-approved peptides have decades of clinical use