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The study demonstrates that in the aortas of atherosclerotic mice, circular RNA circMETTL14 (11)S plays a crucial role in upregulating METTL14 expression and activates METTL14 transcription by binding to the transcription factor SOX2, thus enhancing METTL14-driven m6A methylation and stability of C-X-C chemokine receptor type 4 (CXCR4) mRNA