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These reactions serve as crucial metabolic nodes bridging mitochondrial -oxidation with ketogenesis

Increased the mRNA levels of pro-inflammatory cytokines, tumour necrosis factor partially and reduced anti-inflammatory IL-4/13A, IL-10, IL-11 and TGF-1 mRNA levels partially in association with target of rapamycin (TOR) signaling

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Melatonin is also antiestrogenic and antioxidant

European Society for Medical Oncology website

doi: 10.3390/IECN2023-15970 512 Al-ShaikhMAAl-MufarrejSIMogawerHH