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120,121 ROS are also produced via the metabolism of arachidonic acid by lipoxygenases in the presence of NADH or NADPH

Limited ability to block infections What has become clear is that first-generation vaccines are somewhat limited in their ability to prevent infections, with an efficacy of ~75% for preventing symptomatic infections but only ~45% for preventing asymptomatic infections [5]

[DOI] [PMC free article] [PubMed] [Google Scholar] 54.Cerk IK, Salzburger B, Boeszoermenyi A, Heier C, Pillip C, Romauch M, et al

It's a catastrophic error

Conversely, if you accidentally add extra water, every dose is weaker

But even the strictest regulatory environments struggle against a supply chain that originates in Chinese synthesis facilities, transacts in cryptocurrency, and routes through multiple jurisdictions