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10.1038/s41380-022-01842-x 38 BercikP.DenouE.CollinsJ.JacksonW.LuJ.JuryJ.et al

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In some cases, excess skin or other tissue can be removed to improve the contours and make up for lost elasticity

Preliminary results from the SURPASS-J-mono study in Japanese patients with T2D who were either therapy nave or on an antidiabetic monotherapy showed a head-to-head comparison of a tirzepatide treatment compared to therapy with the GLP-1RA dulaglutide at a dose of 0.75 mg (54, 76)

Melanin is the biochemical compound which is known to produce a tan on the epidermis and hence gives a dull appearance to the skin