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Environ Toxicol Chem 23:25872593 Ruus A, Sandvik M, Ugland KI, Skaare JU (2002) Factors influencing activities of biotransformation enzymes, concentrations and compositional patterns of organochlorine contaminants in members of a marine food web

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The 72-hour minimum gap between any two injections prevents plasma drug levels from stacking to supratherapeutic concentrations, which increases the risk of GI adverse events (nausea, vomiting, diarrhea) that are already the most common reason patients discontinue GLP-1 therapy

The reason for this comes down to where the GLP-1 receptors actually are

dos Santos JF, Alvarez-Lorenzo C, Silva M, Balsa L, Couceiro J, Torres-Labandeira JJ, et al

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