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Rotate injection sites to avoid lipohypertrophy (fat-pad buildup)

Our professional conclusion is this: No, not directly

You further agree that all research will be conducted under appropriate supervision and biosafety conditions

In particular, elective procedures with high consequence complications, including TJA, warrant carefully designed observational cohorts with validated patient-reported outcomes, wound surveillance, and adverse event monitoring

Conversely, inhibiting NNMT allows existing NAD+ (or NAD+ from moderate precursor supplementation) to accumulate, potentially restoring NAD+-dependent pathways more effectively than precursor supplementation alone