Myostatin inhibitorscomprising direct agents such as monoclonal antibodies and small molecules, as well as indirect modulators including follistatin-based strategies and other pathway regulatorshave demonstrated encouraging results in preclinical and early clinical studies by increasing muscle mass and improving muscle function
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Retatrutide doses typically increase during this period, amplifying appetite suppression and metabolic effects
The amylin receptor agonist class represents yet another complementary approach, and combinations like cagrilintide paired with semaglutide (CagriSema) are in late-stage development
