Through intact skin, permeation was near zero (Li et al., 2015)
This issue has not yet been resolved
Researchers observed that GHK-Cu influences expression of over 4,000 human genes based on microarray studies, with significant effects on genes involved in collagen synthesis, metalloproteinase regulation, antioxidant defense (SOD, glutathione), and growth factor signaling (TGF-, VEGF, FGF)
In fact, a study involving 45 adults with chronic kidney disease found that taking 200 mg of selenium daily for three months led to a significant increase in their glutathione peroxidase levels
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Temperature fluctuations, light exposure, or contamination can shorten effective life significantly