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Among these metabolites, TMAO, LPS, and SCFAs play important roles

To the possible persistence of the initial pathogen that triggered the PAIS, one should add the reactivation of latent viruses such as EBV, HHV-6 or VZV (8285), all frequently observed in PAIS, possibly as a result of a reduced efficiency of their control by the immune system

223,224 NADs can be precisely modified to improve their efficacy and stability while decreasing toxicity and immunogenicity

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