Key Structural Differences# Head-to-Head: LEAD-6 Trial# The LEAD-6 trial (Buse et al., Lancet 2009) directly compared liraglutide 1.8 mg once daily with exenatide 10 mcg twice daily in 464 adults with type 2 diabetes inadequately controlled on metformin, sulfonylurea, or both over 26 weeks: Liraglutide was statistically superior for glycemic control and demonstrated better tolerability, with less persistent nausea and fewer hypoglycemia events
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Here are the facts about this medication and one of the reported side effects
After 3 weeks Im down a few pounds and my appetite and craving are going down
This specific dosing strategy was designed and tested for optimal weight loss outcomes
Semaglutide is considered to be safe and effective when used as indicated, but like any weight loss medication, safe doesnt mean that there arent risks