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Singh emphasized that the phenomenon appears tied to rapid HbA 1c reduction rather than direct retinal toxicity from the drug itself

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Potential injection site reactions Compounded formulations sometimes cause more injection site irritation than single-ingredient products

Additional reports have linked the substance to serious adverse health effects, including systemic toxicity and muscle damage

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Some research suggests DSIP directly influences growth hormone secretion beyond just improving sleep quality, though this remains an area of active investigation