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Data Extraction Out of the initial 4482 reports collected through electronic search, 1370 were omitted due to duplication, 74 were excluded based on article type, and an additional 1810 were excluded as they comprised conference abstracts, books, book chapters, and unpublished results

Urology 62, 353356

Signs of thyroid problems (neck swelling, difficulty swallowing, persistent hoarseness) require prompt medical review Symptoms of gallbladder disease (right upper quadrant pain, jaundice, fever) Acute kidney injury symptoms (marked reduction in urine output, swelling, confusion), which can occur secondary to severe dehydration A comprehensive clinical assessment should include review of blood glucose monitoring, assessment for anaemia (full blood count), thyroid function tests, renal function, and evaluation of nutritional status

This swift drop in fat volume leaves the stretched outer tissue with no support

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In the SURMOUNT-1 trial, participants taking the highest dose (15 mg) of tirzepatide lost an average of up to 20.9% of their body weight over 72 weeks