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MT2 receptor expression has been identified in various tissues and organs, such as the immune and reproductive systems, brain, hypothalamus/SCN, retina, pituitary gland, blood vessels, reproductive cells and tissues, testes, kidneys, GI, mammary gland, adipose tissue, and skin

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doi: 10.4103/1673-5374.241445 188 MurakamiT.IlievaH.ShioteM.NagataT.NaganoI.ShojiM

It should be removed for cleaning and routine hygiene practices to prevent infection and check for any ulceration