In the hectic world of nutraceuticals, this is the question that follows millions of people wanting to be healthy through vitamins, minerals, and bioactive compounds
It is noteworthy that, although Vitamin D supplementation within the recommended intake range is generally safe, Vitamin D intoxication has increasingly drawn attention in the context of prolonged or intermittent high-dose regimens, with severe hypercalcemia as the central mechanism leading to neurological, gastrointestinal, cardiovascular, and renal complications [267]
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Those unable to maintain consistency Oral therapies require daily (or structured intermittent) dosing, while topical therapies demand regular application and attention to volume and frequency
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