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An overdose of Bedoyecta can cause impaired liver and kidney function

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In about 17,600 adults with obesity and established cardiovascular disease but no diabetes, semaglutide cut major cardiovascular events by 20% over roughly 40 months. This is a secondary-prevention result in people who already had heart disease

Mecobalamin should be used with caution in individuals with a history of heart disease, particularly if they are at risk for arrhythmias, as large doses may cause changes in heart rhythm

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