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If the cell cannot recycle GSSG back into GSH fast enough using an enzyme called glutathione reductase, the cell enters a state of toxic oxidative stress, leading to mitochondrial damage and, eventually, programmed cell death (apoptosis)
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Vet Immunol Immunopathol 139:308312 Conejeros I, Jara E, Carretta MD, Alarcn P, Hidalgo MA, Burgos RA (2012) 2-Aminoethoxydiphenyl borate (2-APB) reduces respiratory burst, MMP-9 release and CD11b expression, and increases l-selectin shedding in bovine neutrophils
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