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Consistently, in a more recent meta-analysis of 40 randomized controlled trials performed in patients with T2DM, compared with standard diabetes therapies (i.e., metformin, sulfonylureas, insulin, DPP-4i, thiazolidinediones) and placebo, GLP-1RA therapy was associated with significant reductions in inflammatory markers such as serum C-reactive protein (CRP) and TNF-, and a significant increase in adiponectin [80]
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Espinet Coll E, Vila Lolo C, Daz Galn P, et al
Epithelial cell adhesion molecule overexpression regulates epithelialmesenchymal transition, stemness and metastasis of nasopharyngeal carcinoma cells via the PTEN/AKT/mTOR pathway
Mounjaro and Zepbound both contain tirzepatide, a dual GIP and GLP-1 receptor agonist