In several organ systems, at least part of the benefit appears to occur before major weight loss or independent of the number on the scale
That's months of progressive overload
Is Rapid Weight Loss Always Better
Insufficient dosing is perhaps the most common issue
Add a medication that further slows digestion and you create the perfect storm for: Bloating Nausea Sloshing stomach Vomiting Inability to absorb carbohydrates quickly enough If Your Gut Is Slower, Then Your Fuelling Strategy Must Change If you are using a GLP-1 medication while training: Practise race nutrition more frequently Use smaller, more frequent carbohydrate doses Avoid suddenly increasing carb targets Trial lower fibre pre-training meals Start fuelling earlier in sessions before fatigue compounds gut stress And importantly, stop relying on feeling hungry as your cue to eat
In simple terms, semaglutide targets one hormone that makes you feel full and controls blood sugar, while tirzepatide targets two hormones that are shown to have greater improvements in metabolic health, including better insulin sensitivity and fat burning
