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Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial

These are serious complications that every physician and patient must consider when beginning GLP-1 medications

doi:10.1136/bmj-2023-076410 Almandoz JP, Wadden TA, Tewksbury C, et al

Obesity has been implicated as promoting cardiovascular disease, diabetes, hypertension, and other complications, suggesting that sustained, effective weight loss may have independent cardiovascular benefit [13] [14]

Delivering GLP-1 medications through the skin isnt currently feasible, making patches an ineffective delivery method for this class of drugs

The benefits of GLP1 receptors in cardiovascular diseases