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That trial enrolled 338 adults with obesity or overweight without type 2 diabetes, randomized across placebo and four retatrutide dose levels (1 mg, 4 mg, 8 mg, 12 mg weekly), and followed participants for 24 weeks

Market Trend Report Employer Approaches to GLP-1 Coverage December 15, 2025 PHTI For employers, glucagon-like peptide-1 receptor agonists (GLP-1s) for obesity represent an unprecedented healthcare challenge

NICE-appraised licensed alternatives such as semaglutide (Wegovy) and liraglutide (Saxenda) are available through regulated UK weight management services

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And create a simple daily routine that makes consistent eating habits easier to maintain