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Purification of CTR/AMYR-DNGs complex in complex with peptide ligands High-titre baculovirus was generated by transfecting recombinant bacmid (CTR, RAMP and DNG s ) or plasmid (G12) into Sf9 cells using the Bac-to-bac baculovirus system (Invitrogen)

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As opposed to traditional chemotherapy that works by directly destroying rapidly dividing cells, irAEs occur when increased activation of immune effector cells/mechanisms result in damage to normal cells

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