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Why lifting is non-negotiable in midlife or ever Preserve muscle during weight loss: When you lose weight, you always lose some muscle along with fat
It should deliver meaningful amounts of the nutrients women are most likely to need, in forms the body can actually use
The potential health risks to athletes using semaglutide, without genuine medical need through obesity, are sufficient in isolation to satisfy the second criterion of the WADA Code
Sources Comparative review of semaglutide and tirzepatide mechanisms (Pharmacological Research, ScienceDirect) A Contemporary Rationale for Agonism of the GIP Receptor in the Treatment of Obesity (Diabetes, American Diabetes Association) GIP Receptor Agonism Attenuates GLP-1 Receptor Agonist-Induced Nausea and Emesis in Preclinical Models (PMC) Anorectic and aversive effects of GLP-1 receptor agonism mediated by brainstem CCK neurons, modulated by GIP (PMC) Head-to-Head Trial Compares Weight Loss Drugs (Weill Cornell Medicine Newsroom, reporting NEJM SURMOUNT-5) Head-to-head comparison of tirzepatide and semaglutide for weight loss: systematic review and meta-analysis (PubMed) Are You a GLP-1 Nonresponder
Published trials in Obesity (2021) demonstrated mean weight reductions of approximately 10.5kg over 68 weeks, but this average masks substantial person-to-person variation in response
A recent survey conducted by Tebra, a health research firm, found that out of 640 GLP-1 users, 36% reported microdosing the medication
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