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10.1016/j.reprotox.2013.08.005 30

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Its interaction with secondary pathways has been proposed, further extending its theoretically relevant implications when exploring diverse physiological systems

GLP-1 RAs regulate immune cell signaling, suppress proinflammatory cytokines (including tumor necrosis factor alpha (TNF), interleukin-6 (IL-6), and interleukin-1 beta (IL-1)), enhance anti-inflammatory cytokines (interleukin-10- (IL-10)), and decrease reactive oxygen species

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For our patients with type 2 diabetes, tirzepatide lowers blood sugar by enhancing insulin sensitivity and increasing insulin secretion after meals