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Decidual cell reaction: Insight into mechanisms and regulatory factors involved
Beyond cancer biology, DES(1-3) IGF-1 has been investigated in neuroprotection models, where its high potency and reduced IGFBP binding facilitate clean receptor activation in brain tissue preparations where IGFBP concentrations would otherwise limit native IGF-1 activity
Studies published in Nature and Diabetes journals have shown NNMT expression levels correlate with adipocyte hypertrophy and reduced insulin signalling
PubMed Central , Nutrients , vol
Zhou L, Zhang R, Yang S, Zhang Y, Shi D