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Int J Tryptophan Res 7:1522

Now, invert the vial and draw your desired amount of bacteriostatic water (e.g., exactly 2mL) into the syringe

Peroxynitrite is highly toxic to neurons and causes hyper-excitability of the central nervous system, a process known as "kindling." This leads to autonomic nervous system dysfunction (dysautonomia), sensory overload, and severe cognitive deficits

Gradual withdrawal of therapy is recommended

However, a systematic CSF-related dilution would be expected to affect all metabolites proportionally, which is not consistent with the heterogeneous pattern observed in the present study