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First, the intron-poor structure might allow their fast rate of transcription and a rapid adaptation to a changing environment (Jeffares et al., 2008), which might be one of the potent mechanisms modulating the rate of adult neurogenesis
The importance of being CG-rich and the curious case of Sox2 Transcription factors involved in adult neurogenesis are single-exon genes, for example, Sox2 , Sox4 , and Sox11 , or two-exon genes, for example, Ngn2 , NeuroD1, and NeuroD2 , that are embedded in long stretches of high CG densities (CpG islands)
Following cancer treatment, these womens ability to preserve their ovarian reserve at reproductive age has a direct impact on any future infertility issues