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Glutathione primarily functions as an antioxidant, helping protect cells from damage caused by external factors such as UV exposure, pollution, and stresskey contributors to dull and uneven skin tone (Dermatol Surg J, 2022)

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MECHANISM CATEGORIES RESEARCH CONDITIONS SAFETY Side effects Limited human safety data Animal studies report wide therapeutic window Known interactions Methyl-donor depletion theoretical with chronic dosing (NNMT methylates nicotinamide using SAM) Contraindications Pregnancy/lactation (unstudied) REGULATORY STATUS FDA Not FDA-approved

systematic rotation is essential to prevent lipohypertrophy and ensure consistent absorption