Life Sci 264:118645 Yaribeygi H, Maleki M, Butler AE, Jamialahmadi T, Sahebkar A (2022a) New insights into cellular links between sodiumglucose cotransporter-2 inhibitors and ketogenesis
This is usually stress response to rapid weight loss and caloric restriction (telogen effluvium), not direct medication effect
Semaglutide treatment produces sex-dependent remodeling of adipose and muscle masses in ob/ob mice Our previous study showed that semaglutide-induced weight loss was accompanied by reductions in both fat and lean mass
Liu S, Gad M, Li C, et al
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One practical implication: if pregnancy is a goal within the next 12 months, many prescribers recommend either delaying tirzepatide initiation or choosing a shorter-acting weight loss protocol