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Contact your provider if you experience intractable vomiting (unable to keep down fluids for more than 24 hours), severe abdominal pain (particularly if constant or radiating to the back), or signs of dehydration including decreased urination, extreme thirst, dizziness, or confusion

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Provider assessment of baseline B12 status via serum cobalamin and methylmalonic acid is standard before initiating protocols

Take three measurements and average them

However, lipotropic injections are not a miracle solution for losing weight when taken on their own

A 2025 human pilot study reported no adverse cardiac, hepatic, or renal effects at IV doses of 10-20mg