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The authors synthesized evidence that HGF/c-Met signaling is essential for brain development, synaptic plasticity, and cognitive function, with disruption of this pathway associated with cognitive decline in aging and neurodegenerative diseases

Exendin-4, a GLP-1R agonist, also suppressed basal expression of several inflammatory mediators and in combination with phosphodiesterase inhibitors, decreased CXCL10 expression by IFN- (a type II-interferon) in human islets and in MIN6 cells (a mouse -cell line)

Weight loss has long been recognized as an effective strategy to reduce OSA severity

Physician oversight requirements

Curr Opin Food Sci 19:113119

This is particularly relevant for patients on corticosteroids, other hormone therapies, or medications that affect endocrine function