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Any patient currently on tirzepatide 15 mg who wants to trial retatrutide should discontinue tirzepatide first, allow at least two weeks for GI recovery, and begin retatrutide at the 2 mg starting dose with standard titration [2][4]

Chinese bulk sourcing exists because this market need is real and the Western supply chain does not address it efficiently

The formula is straightforward

This is not specific to retatrutide but occurs with any aggressive caloric deficit or weight loss intervention

Suspected adverse reactions to any substance should be reported via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk

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