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First, we excluded case and non-case reports with gastrointestinal events (all PTs belonged to gastrointestinal disorders in the system organ class) in the dataset

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Biochem Biophys Res Commun 298:779784 Mulherin AJ, Oh AH, Kim H, Grieco A, Lauffer LM, Brubaker PL (2011) Mechanisms underlying metformin-induced secretion of glucagon-like peptide-1 from the intestinal L cell

An earlier study suggested that IGF-1-mediated stimulation of proliferation might act through transcriptional regulation [51]

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The influence of DEM on nAchR and GST3 was different in the mutual exposures with the two neonicotinoids