doi: 10.1016/j.cbi.2024.110956 70 GeXGuYWangWGuoWWangPDuP
Look for glycerin, hyaluronic acid, ceramides, aloe vera, panthenol, or shea butter
Aardvark Therapeutics Sector: Oral gut-restricted bitter taste receptor agonists for hunger suppression HQ: San Diego, CA Year Founded: 2017 Origin Story: Aardvark Therapeutics was founded around a mechanistically distinct hypothesis: rather than suppressing appetite like GLP-1 drugs, the companys lead compound activates bitter taste receptors (TAS2Rs) confined to the gastrointestinal tract to trigger local release of satiety hormones, targeting hunger itself without systemic drug exposure
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These genomic research applications position Pinealon as an invaluable tool for advancing our understanding of gene regulation, aging mechanisms, and the development of targeted interventions for promoting healthy aging and longevity
doi: 10.1172/jci.insight.123182 172 LiuZ.RenZ.ZhangJ.ChuangC.-C.KandaswamyE.ZhouT.et al