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In response, CMS identified three DSNP model designations: Coordination Only DSNPs (CO-D-SNPs), Highly Integrated Dual Eligible Special Needs Plans (HIDE-SNPs), and Fully Integrated Dual Eligible Special Needs Plans (FIDE-SNPs) (Figure 1)

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These changes in protein expression bring about the fragmentation of mitochondria and their accumulation around the nucleus, which might deprive dendrites and axons of mitochondria [318]