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Prednisolone is a corticosteroid used to treat inflammatory and autoimmune conditions, whilst Wegovy (semaglutide 2.4 mg) is a GLP-1 receptor agonist licensed for chronic weight management in specific patient groups

These options support clients struggling with malabsorption, making nutrient delivery direct and effective

Patients who were initiated on metformin concurrently with GLP-1RA were the better metabolic responders after adjustment for BMI, fat mass index, insulin, and diabetes duration, indicating concurrent initiation is the more effective clinical approach

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Although earlier studies suggest no agerelated decline in GH responsiveness to GHRH, more recent reports indicate a gender-independent, age-related decline in acute GH responsiveness to GHRH and ghrelin (16)