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Current research (such as studies indexed in PubMed regarding Short-Chain Fatty Acids and Incretin Secretion ) highlights that when gut bacteria ferment these specific fibers, they produce metabolites like butyrate and propionate

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Given low event rates, the primary analysis was changed mid-trial to a win ratio analysis of a hierarchical composite of CV plus cardiometabolic outcomes resulting in more wins for dapagliflozin (win ratio, 1.34

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It does not mean the medication has failed

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