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During measure development, volume bands of 20,000 visits were chosen based on existing literature and actual use within the ED measurement and quality community, such as the ED Benchmarking Alliance

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These include: Renal impairment impaired kidneys cannot clear excess magnesium and other minerals safely G6PD deficiency high-dose vitamin C can trigger haemolytic anaemia in these patients Congestive heart failure fluid overload risk with IV administration

Ajit, Exosome microRNA signatures in patients with complex regional pain syndrome undergoing plasma exchange

Glutathione is sensitive to oxidation

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