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Additionally, sodium-glucose cotransporter 2 (SGLT2) inhibitors, known for their glycemic and cardiovascular benefits, when combined with incretin-based therapies, have demonstrated additive improvements in weight loss, glycemic control, and liver function markers

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Potential limitations: Some primary care providers prefer to refer GLP-1 prescriptions to specialists

Achieving sufficient drug concentration in the myocardium is difficult, as reactive oxygen scavengers tend to have short plasma half-lives and may not accumulate at injury sites [376]