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Randomized study of metformin and intensive lifestyle intervention on cancer incidence over 21 years of follow-up in the diabetes prevention program

J Neuroimmunol, 28: 14-26

[2] [10] The low risk of hypoglycaemia when used as monotherapy or with metformin is another important benefit, as the glucose-dependent mechanism of insulin secretion means these medicines do not typically cause dangerously low blood sugar levels

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