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The major source of ROS comes from non-enzymatic processes in the mitochondrial respiratory chain (22)

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GGCT affects the proliferation by disrupting the redox balance in tumor cells To explore the biological function of GGCT, we analyzed transcriptome data by knocking down GGCT in MHCC97H cells (GSE282603) and compared it with the published data from PC3 cells (GSE154584)

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2007 reported that GHK-Cu stimulated dermal papilla cell proliferation by up to 70% in vitro and was associated with an extended anagen phase in their model

The stroma can restrain tumor expansion, shape immune exclusion, regulate vascular compression and influence invasion patterns [13, 17, 70, 97]