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These monotherapy results established proof of concept that amylin receptor agonism alone can produce clinically meaningful weight reduction and informed the dose selection of 2.4 mg for the combination product CagriSema
Cochleae are then rinsed in PBS-T and incubated in the appropriate fluorescent secondary antibodies in PBS-T with 10% goat serum for 2 hrs at room temperature
However, it is not all rosy news with this protein
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