CANVAS demonstrated a 14% reduction in MACE in patients with T2DM and a high cardiovascular risk (54, 57)
Initially developed as glucose-lowering therapies, both classes have shown impressive cardiovascular and kidney-protective effects [17,18]
Holistic support services will be critical to successful long-term outcomes
Zheng S, Huang H, Chen H, Liu Y
At week 26, LDL-C was reduced by 19.0% (-36.0% to -1.9%, p=.029) in the tirzepatide 15 mg group compared to placebo while it was reduced by 17.8% (-33.7% to -2.0%, p= 0.028) in the dulaglutide 1.5 mg group compared to placebo though differences between the 2 medications were not seen [60]
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